Iso-Clear Intro
Iso-Clear Intro

CAITLIN

IN-HOUSE CONTENT CREATOR AND ISOCLEAR™ PATIENT

Month 0
Month 3
Iso-Clear Intro

The Future of Acne Care

  • (01)Targets active breakouts
  • (02)Reduces visible dark spots
  • (03)Supports skin renewal
Iso-Clear Intro

Backed by Clinical Evidence

  • (01)5 weeks to visible acne improvement*
  • (02)8 weeks to smoother, clearer-looking skin*

*Based on published clinical research

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INTRODUCING

Rx

Isoclear™/ i-so-clear /

A dermatologist-backed topical Isotretinoin system (active ingredient in Accutane) designed to treat acne, fade marks, and maintain clear skin - without the complexity of oral treatments.

  • Targets acne at the source
  • No monthly lab tests required
  • Designed for real-world consistency

$50/mo

What makes Isoclear™ different?

It’s not just a product, it’s a complete acne system. Isoclear™ treats active breakouts at the source, then supports your skin through fade and maintenance, all in one simple, guided approach.

Who is this best suited for?

Perfect for anyone dealing with ongoing breakouts, oily skin, or acne that keeps coming back-and wants a complete, start-to-finish solution instead of switching between products.

What results can I expect?

Fewer breakouts, reduced oil, and clearer skin over time, plus a routine designed to help you stay clear, not just treat acne once.

This product is a compounded formulation prepared by a licensed pharmacy pursuant to Section 503A of the Federal Food, Drug, and Cosmetic Act. Compounded medications are not FDA-approved, meaning they have not been evaluated by the FDA for safety, effectiveness, or quality. Licensed medical providers may prescribe compounded preparations at their professional discretion based on an individual patient’s needs. This product is intended for use only under medical supervision.

The Isoclear™ system

A personalized approach to clearer skin. Start with your primary concern - acne, marks, or anti-aging and let Isoclear™ adjust to your needs.

CLEAR
Step 1
CLEAR
FADE
Step 2
FADE
RENEW
Step 3
RENEW
CLEAR
Isoclear™

CLEAR

PHASE 1 • 0-4 MONTHS

Target breakouts at the source.

The Clear phase focuses on active breakouts at the source, helping to regulate sebum production, increase cellular turnover, and fight bacteria and inflammation.

The Formula
Isotretinoin

Isotretinoin

A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.

Isoclear™

CLEAR

PHASE 1 • 0-4 MONTHS

BEST FOR
Active acne, clogged pores, excess oil, and recurring breakouts
WHAT IT DOES
Helps clear active breakouts, regulate oil production, calm inflammation, and prevent future flare-ups
KEY INGREDIENTS
Isotretinoin + Antibacterial Support (Clindamycin)
WHAT TO EXPECT
Visible improvement over weeks with use. Skin gradually becomes clearer and more balanced
FADE
Isoclear™

FADE

PHASE 2 • 4-6 MONTHS

Fight post-acne marks and uneven skin tone.

The Fade phase targets post-inflammatory hyperpigmentation (PIH) once breakouts clear, while evening out skin tone for a uniform glow.

The Formula
Isotretinoin

Isotretinoin

A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.

Isoclear™

FADE

PHASE 2 • 4-6 MONTHS

BEST FOR
Post-acne marks, uneven skin tone, and lingering pigmentation
WHAT IT DOES
Helps fade post-acne marks, brighten uneven skin tone, and support a clearer, more even complexion
KEY INGREDIENTS
Isotretinoin + Niacinamide + Tranexamic Acid
WHAT TO EXPECT
Dark marks gradually begin to fade while skin looks brighter, smoother, and more even over time
RENEW
Isoclear™

RENEW

PHASE 3 • 6 MONTHS +

Where clear skin becomes great skin.

Keep breakouts at bay while improving skin texture and renewing your skin’s vitality with a peptide complex and GHK-Cu (Copper Peptide).

The Formula
Isotretinoin

Isotretinoin

A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.

Isoclear™

RENEW

PHASE 3 • 6 MONTHS +

BEST FOR
Maintaining clear skin, improving skin texture, and supporting long-term skin renewal
WHAT IT DOES
Helps keep future breakouts under control while improving skin texture, smoothness, and overall skin quality
KEY INGREDIENTS
Isotretinoin + GHK-Cu + Peptide Complex
WHAT TO EXPECT
Skin looks smoother, healthier, and more refined over time, with continued support for long-term clarity and renewal

The Isoclear™ system

A personalized approach to clearer skin. Start with your primary concern - acne, marks, or anti-aging and let Isoclear™ adjust to your needs.

CLEARFADERENEW
1
2
3
Isoclear™

CLEAR

Isoclear™

FADE

Isoclear™

RENEW

PHASE 1 • 0-4 MONTHS

PHASE 2 • 4-6 MONTHS

PHASE 3 • 6 MONTHS +

Target breakouts at the source.

Fight post-acne marks and uneven skin tone.

Where clear skin becomes great skin.

The Clear phase focuses on active breakouts at the source, helping to regulate sebum production, increase cellular turnover, and fight bacteria and inflammation.

The Fade phase targets post-inflammatory hyperpigmentation (PIH) once breakouts clear, while evening out skin tone for a uniform glow.

Keep breakouts at bay while improving skin texture and renewing your skin’s vitality with a peptide complex and GHK-Cu (Copper Peptide).

The Formula
Isotretinoin

Isotretinoin

A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.

The science behind the Isoclear™ system

Topical Isotretinoin has been studied both domestically and internationally for acne, skin clarity, and photoaging. Isoclear™ delivers this active through a multi-phase treatment system and customized gel bases designed for comfort and long-term use.

01

Fights Acne at the Source

Reduces pimples, blackheads & whiteheads - clears skin within weeks.

View study →
02

Gentle on Skin

Minimal absorption, fewer side effects - no lab tests required.

View study →
03

Dual Action Power

Targets acne while improving texture, tone & early signs of aging.

View study →
1

Fights Acne at the Source

Reduces pimples, blackheads & whiteheads - clears skin within weeks.

View study →
3

Dual Action Power

Targets acne while improving texture, tone & early signs of aging.

View study →
Iso-Clear Cream Swatch
2

Gentle on Skin

Minimal absorption, fewer side effects - no lab tests required.

View study →
Clinical studies referenced are based on the active ingredient, Isotretinoin, and not this specific compounded formulation. Compounded formulations are not FDA-approved. Some studies shown may reference branded products that may be marketed outside of the United States. Patients should not use Isoclear™ during pregnancy or if they plan on becoming pregnant.
Clinical studies referenced are based on the active ingredient, Isotretinoin, and not this specific compounded formulation. Compounded formulations are not FDA-approved. Some studies shown may reference branded products that may be marketed outside of the United States. Patients should not use Isoclear™ during pregnancy or if they plan on becoming pregnant.
Topical Isotretinoin Results

Significant improvement in as few as 5 weeks*

Weeks to statistically significant improvement vs. placebo, 268-patient trial

Time to statistical significance for three outcomes in Chalker 1987 Week 5Week 8Week 8Active breakoutsPapules & pustulesBlackheads & whiteheadsNon-inflammatory lesionsOverall acne severityClinical severity gradeStartWeek 3Week 5Week 8Week 10 +Filled = time to reach statistical significance vs. placebo - Track = 14 - week treatment period
Time to statistical significance - mobile versionWeek 5Week 8Week 8Active breakoutsPapules & pustulesBlackheads &whiteheadsNon-inflammatorylesionsOverall acne severityClinical severity gradeStartWeek 5Week 8Week 10 +Filled = time to reach statistical significance vs. placeboTrack = 14 - week treatment period

Chalker DK, Lesher JL, Smith JG, et al. J Am Acad Dermatol. 1987;17(2):251–254. Multicenter, double-blind, vehicle-controlled trial of topical isotretinoin 0.05% gel (N = 268). View Study Individual results may vary.

*Data shown is derived from studies on topical isotretinoin formulations in clinical settings, not Isoclear™ specifically.

Isoclear™ - DESIGNED TO FIT YOUR LIFE.

TOPICAL ISOTRETINOIN VS. TRETINOIN*

Better tolerability, less irritating than standard Tretinoin

Two clinical advantages - measured head-to-head.


% of users reporting stinging, erythema, or desquamation

Tretinoin
67%
Topical Iso
47%
Tretinoin
67%
Topical Iso
47%
~30% less irritation reported
WHERE IT WORKS*
TRETISO
Cell turnoverUnclogs pores at the surface
Mechanistically targets oil productionTargets sebaceous activity

Bouchelkia I, Tyring S. Topical Isotretinoin: Current Applications, Challenges, and Future Directions. Cureus. 2025 Aug 23;17(8):e90820. doi: 10.7759/cureus.90820. PMID: 40995273; PMCID: PMC12455260. View Study Individual results may vary.

*Data shown is derived from studies on topical isotretinoin formulations in clinical settings, not Isoclear™ specifically.

Video thumbnail

Isoclear with Dr. Aaron Farberg -

From Acne to Anti-Aging in 3 Steps

Isoclear with Dr. Aaron Farberg - From Acne to Anti-Aging in 3 Steps
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From Breakouts to Clear Skin

0–4 Months: Clear PhaseClear active acne at the source

Your treatment begins reducing active breakouts, excess oil, clogged pores, and visible inflammation. Skin starts feeling calmer, less congested, and more balanced over time.

This phase builds the foundation for long-term skin clarity.

4–6 Months: Fade PhaseFade post-acne marks and uneven tone

As active acne improves, leftover redness, dark spots, and post-acne marks gradually begin fading. Skin texture starts appearing smoother while overall tone looks more even and refined.

This phase helps reveal brighter, healthier-looking skin.

6+ Months: Renew PhaseRenew skin confidence long term

Your skin reaches a healthier, more stable state with continued support for clarity, texture, and long-term balance. Ongoing maintenance helps keep results consistent over time.

Clear acne at the root

Access personalized treatment, prescription management, and ongoing support, all in one streamlined plan.

Simple, transparent pricing

Clear, upfront pricing with no hidden fees or surprise charges, so you always know exactly what's included in your treatment plan.

Ongoing monitoring & treatment adjustments

Track your acne journey with progress photos, treatment check-ins, and access to your intake history throughout care. If your doctor recommends changing or adjusting your treatment, it's included at no additional consultation cost.

No insurance required

Get access to expert acne treatment without insurance, referrals, or in-person appointments.

Flexible payment options available

Choose a payment option that fits your budget. Affirm financing with 0% APR options is available on eligible plans.

Access across all 50 states

Get expert dermatology care from anywhere in the U.S., with no in-person visits required.

The Clear Health Guarantee

Not seeing the results you want with Isoclear™ after 4 months? We'll help you step up to oral Accutane or an alternative treatment if appropriate - including your first month's consult and medication FREE on us (up to a $174 value).

Bi-Monthly

Everything for your treatment, in one price

$50/mo

Starting with a 2-month supply

INCLUDES$59 Value
Dermatologist Evaluation$59Free
Get a treatment plan in <24 hours
Unlimited support from clinical team
Free shipping directly to your door
For the Fade or Renew Phase of Isoclear™, 3-month supply options are available.

Isoclear™ vs. Oral Isotretinoin (Accutane) - what's right for you?

From active breakouts to lingering marks, not all treatments work the same. Compare how each approach targets acne, oil, and long-term skin health.

Comparison

Targets Root Cause

Targets Marks & Texture

No iPLEDGE Required

No Monthly Check-ins

No Lab Tests Needed

(Clear Health)

Iso Clear

Isoclear™

All-in-one system starting at $50/mo

(Generic Platforms)

Other Topicals

Other Topicals

$60–$100+/mo across multiple products

(Clear Health)

Isotretinoin

Accutane

Starts from $59/mo (Evaluation Only)

Swipe to compare

A Laddered Approach -
The Clear Health Guarantee

We get it – starting a new acne treatment can be full of uncertainty and questions. Will it work for you? How long will results take?

Our goal is to get you clear. If you use Isoclear™ for at least 4 months and aren’t seeing the progress you want, we’ll help you step up to oral Accutane - on us to get started, including your first month’s consult and medication (up to a $174 value).

A Laddered Approach
In their words

Hear from our patients

See how real patients started Isoclear feeling nervous and skeptical, and what happened next. Straight from them, no scripts.

Clear Health is prescription skincare, made simple.

Prescription Treatments

Access science-backed treatments and custom formulations, proven to work based on research.

Prescription Treatments

Tracking & Digital Care

Track your skin progress over time and stay connected with your care team - every step of the way.

Tracking & Digital Care

Ongoing Medical Care

Personalized care, tracking, and support in one seamless experience. Guided onboarding with expert recommendations to keep you on track.

You

Hi, when should I take my medication?

Dr. Aaron Farberg, MDDoctor

Take it in the morning for best results. Consistency is key - we'll adjust if needed.

Monique KreitzCoordinator

I'll check in every few days to monitor your progress.

Taylor WrightSupport

Need help with your account? Message me anytime, 24/7.

24/7 Unlimited Care & Support

Real treatment needs real support. Get 24/7 access to guidance, so you stay on track and see better results faster.

24/7 Unlimited Care & Support

FAQs

Find out more about Isoclear™
Does Isoclear™ require enrollment in the iPLEDGE® program?
No. Isoclear™ is a compounded topical isotretinoin medication and is not subject to the iPLEDGE® REMS program. Therefore, enrollment in iPLEDGE is not required for patients prescribed Isoclear™.
What ingredients are used in Isoclear™?
Isoclear™ is built around isotretinoin, the same gold-standard ingredient used in Accutane - but applied topically. Depending on your phase, it’s combined with ingredients that help fight bacteria, fade marks, and support skin repair.
How do you use Isoclear™ ?
It’s a simple daily application. You start by treating active acne, then move into fading marks, and finally maintaining clear skin-so you’re not switching between multiple products.
What type of acne does Isoclear™ work for?
It works best for mild to moderate acne-like regular breakouts, clogged pores, and oily skin that keeps flaring up.
What is the IsoClear™ Treatment Assurance?
If, after using Isoclear™ consistently for at least four (4) months, your provider determines that you have not achieved an adequate response, eligible patients may qualify for one follow-up consultation and one month of medication at no additional charge, subject to clinical appropriateness, eligibility requirements, and applicable regulations. Additional terms and conditions apply.
How does the Clear–Fade–Renew system work?
Instead of treating acne once and stopping, Isoclear™ takes you through a full journey-clearing breakouts, fading marks, and helping you stay clear long-term.

Blogs

Blog Image

Why Am I Breaking Out Here? What Pimples on Your Nose, Cheeks, Chin, and Forehead Could Mean

Written by Erika Morrison

Acne can feel random, especially when breakouts keep showing up in the same place. Maybe you keep asking, “Why is my nose breaking out?” or “Why do I keep getting .....

Acne Hormonal Acne

A One-Stop Shop for your Journey

Introducing
Iso-Clear topical bottle
Topical Isotretinoin SystemRx

Isoclear™

Starts at$50/mo

Learn More
Exclusive 1st month's medication included on select plans. Just pay shipping.
Standard protocol treatment box
Accutane (Isotretinoin)Rx

Standard Protocol

Evaluations start at$59/mo

Learn More
Evaluations + medications included on all plans.
Micro-dose protocol treatment boxMicro-dose protocol treatment box
Accutane (Isotretinoin)Rx

Micro-Dose Protocol

1st month starts at$59

Learn More
Jojoba Oil Cleanser
Skincare Item

Jojoba Oil Cleanser

$28

Learn More
Lightweight Moisturizer
Skincare Item

Lightweight Moisturizer

$28

Learn More
Compounded Topical
Topical TreatmentRx

Compounded Topical

from$30/mo

Learn More
Spironolactone + Topical
Oral TreatmentRx

Spironolactone + Topical

$37.50/mo

Learn More
Doxycycline + Topical
Oral TreatmentRx

Doxycycline + Topical

$40/mo

Learn More
At-Home LFT + Lipid Panel Bloodwork Kit
Supporting Product

At-Home LFT + Lipid Panel Bloodwork Kit

$115

Learn More
Home Pregnancy Tests (6 ct)
Supporting Product

Home Pregnancy Tests (6 ct)

$30

Learn More
Aquaphor® (3 ct)
Supporting Product

Aquaphor® (3 ct)

$30

Learn More

Real people with real results

4.6/5 BASED ON 30,000+ PATIENTS

Customer support is on it

D S.

Customer support is on it! Always helping me with things I need and ask. Also, their quick replies are amazing. I m... Read More

My experience has been great so far

Amanda B.

My experience has been great so far! Easy to message my doctor with any questions and I was able to get on Accutane so... Read More

Great Company! Wonderful Services!

D HB.

Very fast and helpful assistance from all staff members. Customer service is always there to assist me and the doctors... Read More

Clear Health has been very responsive…

BIBI.

Clear Health has been very responsive to my questions in a short time span as well as having a very courteous approach.

Amazing and revolutionary acne treatment

Sanjana D.

Its a great and cheap way to get one of the most expensive treatments for acne out there. The support is amazing, they... Read More

Smooth and easy process

MELISS

Smooth and easy process. Especially helpful with clearing hoops like prior authorization and communicating with... Read More

Super responsive customer support

ERICA D.

Super responsive customer support! The experience has been great for my daughter and so much easier than waiting months... Read More

So much easier and quicker than going…

JACKIE M.

So much easier and quicker than going through the in-person experience. This is my 2nd time going on Accutane, and I... Read More

I'm very pleased with Clear Health

Shaban R.

I'm very pleased with Clear Health! Everything was wonderful, from the initial online consultation to the monthly order... Read More

*Individual results vary