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Eligible patients may be prescribed Accutane branded Isotretinoin or its bio-equivalent generic versions depending on pharmacy selection, insurance coverage, and pharmacy stock. The physician overseeing treatment will determine which medications (or substitutions) may be most appropriate.
Eligible patients may be prescribed Accutane branded Isotretinoin or its bio-equivalent generic versions depending on pharmacy selection, insurance coverage, and pharmacy stock. The physician overseeing treatment will determine which medications (or substitutions) may be most appropriate.
Isotretinoin, known widely as Accutane, is the only treatment that can potentially cause permanent remission of acne symptoms, or effectively treat acne “for good”. Most patients experience dramatic results, since Accutane tackles all four primary causes of acne. It:
Isotretinoin, known widely as Accutane, is the only treatment that can potentially cause permanent remission of acne symptoms, or effectively treat acne “for good”. Most patients experience dramatic results, since Accutane tackles all four primary causes of acne. It:
All candidates for Isotretinoin (Accutane) treatment must be enrolled into the FDA’s iPLEDGE program, which mandates certain requirements including pregnancy testing and contraceptive-use for female patients that can get pregnant. Additional requirements during treatment include bloodwork lab orders and monthly check-ins with a physician. If this sounds complicated – don’t worry! We’ll walk you through step-by-step and digitally manage everything you need so you never miss a beat.
IMPORTANT SAFETY INFORMATION FOR ISOTRETINOIN (GENERIC ACCUTANE): Isotretinoin (Accutane) must not be used by patients who are or may become pregnant. There is an extremely high risk that severe birth defects will result if pregnancy occurs while taking Isotretinoin (Accutane) in any amount, even for short periods of time. Potentially any fetus exposed during pregnancy can be affected. There are no accurate means of determining whether an exposed fetus has been affected. Read more about serious warnings and safety info.
Digitally managed process
No insurance required
Convenient and affordable
Online dermatologist consultations
Digitally managed process
No insurance required
Convenient and affordable
Online dermatologist consultations
Thousands of patients treated, astonishingly clear results.
Thousands of patients treated, astonishingly clear results.
4.6/5 BASED ON 10,000+ PATIENTS
I was on accutane for the standard protocol and I had no problems at all. I just finished my treatment. If I had any issues or questions they responded fairly quickly. I would recommend this to anyone who had any problems with acne or their skin. Telia G.
Telia G.
Before starting, my skin was stubborn with constant breakouts that never went away no matter what I tried, from topicals to antibiotics and skincare trends. After a few months on Accutane, my skin completely transformed. I have no active acne now, my face feels smooth, my confidence is up, and I no longer worry about new breakouts. Mika L.
Mika L.
Now that I no longer have to stress about any upcoming breakouts, I can see my true-self when I look in the mirror. Maxwell V.
Maxwell V.
I had been on different antibiotics and topicals for almost a year before discovering Accutane. Three months in and I was already starting to see great results. I can’t wait to finish treatment! Brianna R.
Brianna R.
Accutane has been a life changer. It has changed my confidence and my entire life. I am so happy that I found you!! Luis G.
Luis G.
I haven’t had a breakout in months, my skin is smoother, clearer, and I feel so much more confident. Clear Health made the whole process seamless and stress-free! Joseph L.
Joseph L.
I’ve struggled with acne since I was 14, and Clear Health made my second Accutane journey easy and stress-free. Everything was online, my meds came right to my door, and within months my skin cleared completely. I’ve never felt more confident. Ashley O.
Ashley O.
As a content creator, my skin is always on display. Breakouts made me anxious about filming, but Clear Health changed that. Everything was quick, online, and personalized. A few months later, my skin was clear — and so was my confidence. Holly M.
Holly M.
A year ago, my acne was at its worst. After six months of treatment with Clear Health, my skin is clear, healthy, and I finally feel confident again. Emma G.
Emma G.
I’d tried everything for my acne — nothing lasted. On a road trip, I started Clear Health’s micro-dosing Accutane, and within months, my skin completely transformed. Adam G.
Adam G.
Clear Health made the process simple and stress-free. In just three months, my skin’s smoother, less oily, and breakout-free — finally clear after years of struggling. Marco M.
Marco M.
I needed something easy and effective. Clear Health made Accutane simple and guided me through it. Now my skin’s clear, smooth, and I feel confident every day. Jamery T.
Jamery T.
My acne was at its worst as I started my career, but Clear Health made treatment easy and stress-free. Now my skin is clear, and my confidence is higher than ever! Brooke S.
Brooke S.
When you’ve tried everything and Finally find something that works 🙌 @helloclearhealth Ian H.
Ian H.
*Individual results vary
Isotretinoin (Generic Accutane) Protocols
Standard Protocol
6-7 months treatment
$59
Monthly
Evaluation only
$275
6 Months
Evaluation only
Suitable for moderately severe to severe acne.
Insurance and cash-pay options for medication.
1st month's medication is included on 6-month plans if filling through Clear Health.
Micro-dose Protocol
18-24 months treatment
1st month at $59
then $109/mo
Evaluation + Medication Included
Suitable for mild to moderate forms of acne.
Potentially minimize treatment side effects.
Monthly medications are included on all plans.
PROTOCOL IMPORTANT INFORMATION: Low-dosing Isotretinoin (Accutane) is considered a form of off-label prescribing. The FDA requires that prescription drugs go through a clinical testing process to establish that they’re safe and effective to treat a particular condition. Healthcare providers generally may prescribe the drug for an unapproved use when they judge that it is medically appropriate for their patient. This type of prescribing is called “off-label” prescribing. Off-label prescribing practices are sometimes validated by clinical experience and research and may be a widely recognized clinical practice. Clear HealthTM affiliated providers have the discretion to prescribe drugs off-label based on a patient’s unique medical history, symptoms, and preferences.
Compare & find the treatment for you
SEVERE ACNE
Standard Protocol
6-7 MONTHS
FOR SEVERE ACNE
$59/MO EVALUATION + $95/MO* MEDICATION
INSURANCE AND CASH-PAY OPTIONS
*Medication costs vary. With insurance, costs can be as low as your co-pay. Our cash prices are typically lower than most big-box pharmacies and start at $95/month.
MILD-MODERATE ACNE
Micro-Dose Protocol
18-24 MONTHS
FOR MILD TO MODERATE ACNE
$120/MO EVALUATION + MEDICATION
$50/MO POST-TREATMENT KIT
Standard Protocol
$59/month
includes evaluation only
The standard protocol typically lasts ~6 months, typically targeting a cumulative dosage of 120mg/kg of body weight.
This protocol is ideal for moderate to severe acne, and can sometimes be covered by insurance.
We also offer cash-based medication pricing at 50% of the cost of big box pharmacies and deliver directly to you from our specialty pharmacy.
Micro-dose Protocol
$109/month
includes evaluation + medication
The Clear HealthTM Micro-dose protocol is a low-dose Isotretinoin (Accutane) treatment taken for a longer period of ~18 months.
Also known as "Hollywood dosing", this low dose treatment can potentially minimize the impact of side effects, and is suitable for chronic mild to moderate acne that may not be responsive to traditional acne treatments.
This protocol may also be ideal for second-time Isotretinoin (Accutane) users.
SIDE EFFECTS
Examining the Stigma
You may have heard about the stigma surrounding Isotretinoin (Accutane) and its potential side effects. The truth is, the vast majority of patients only experience things like dry skin or dry lips, and serious side effects are actually quite rare.
That said, we take safety extremely seriously and will be consistently checking in to make sure you're crushing your treatment.
STORE
A One-Stop Shop for your Journey
Exclusive: 1st month's medication included on select plans. Just pay shipping.
Standard Protocol Accutane (Isotretinoin)Evaluations start at $59
Evaluations + medications included on all plans.
Micro-dose Protocol Accutane (Isotretinoin)Starts at $59
Jojoba Oil Cleanser$28
Lightweight Moisturizer$28
Compounded Topical Creamfrom $30/mo
Spironolactone + Topical$37.50/mo
Doxycycline + Topical$40/mo
At-Home LFT + Lipid Panel Bloodwork Kit$115
Home Pregnancy Tests (6 ct)$30/6-pack
Aquaphor® (3 ct)$30/3-pack
Easily navigate a traditionally complex treatment process.
EFFICIENT
Don't wait months for a dermatologist appointment. Start treatment in days.
No PCP referral needed or 3-month waitlist. Get connected directly to a board certified dermatologist in less than 24 hours, no insurance required.
THE OLD ISOTRETINOIN (GENERIC ACCUTANE) JOURNEY
The New journey
THE NEW JOURNEY
Online Evaluation and Seamless Digital Treatment Management
Digitize Complex Pen & Paper Admin Processes
All Prescriptions, Supporting Items and Skincare Delivered
THE OLD JOURNEY
CONVENIENT
Manage everything online. From getting clear to staying clear.
iPLEDGE items, labs, prescriptions, skincare and more, all managed in your digital portal.
Detailed video and SMS onboarding with your clinical team so you never miss a beat.
AFFORDABLE
Get treated at 1/3 the cost.
Use your insurance or choose our cash-pay option and have your prescriptions delivered. Oftentimes, patients find that even with insurance, our cash-pay option is more affordable.
MONTHLY PLAN
$59/month
6 MONTHS PLAN
$275
IN-PERSON
$1,200+from $200/month
ACCESSIBLE
We'll set all the reminders so you don't have to.
Automated monthly SMS check-ins so you're always on top of treatment.
Around-the-clock access to responsive support team.
Around-the-clock access to your physician.
24/7 access to Nurse Advice line.
FAQs
Designed with Experts
Clear Health™ was designed in tandem with some of the leading subject matter experts on dermatology and acne to provide streamlined virtual care for patients around the country.
Board-Certified Dermatologists Our team includes recognized, credentialed clinicians dedicated to increasing access to care.
Acne Solution Innovators Our experts are at the forefront of the latest acne research, bringing fresh insights to help transform skin health.
Patient-Centric Approach The patient experience sits at the center of everything we do.
Dr. Aaron Farberg
Clear Health™ Medical Director
Mohs surgeon and former consultant dermatologist to the NY Yankees.
Icahn School of Medicine at Mount Sinai
Clinical Assistant Professor at UNT Health Science Center
Danielle Samuels PhD
Developmental Psychologist
Developmental psychologist whose research focuses on the intersection between acne, adolescence, and mental health.
Harvard University
Faculty at Laguna College of Art and Design
Science vs. Stigma
Accutane is the only medication known to address all four cases of acne including inflammation, acne bacteria, excess oil production, and slowed dead skin cell turnover. But what’s the truth behind the side effects that everyone talks about?
Specialty Pharmacy vs. Retail: The Clear Health™ Advantage
Getting Accutane through a traditional pharmacy can mean delays, stock issues, and insurance headaches. Clear Health™ partners with FDA-regulated specialty pharmacies that focus on dermatology medications, ensuring reliable access, faster fulfillment, and seamless iPLEDGE compliance.
No unnecessary wait times—just affordable and hassle-free treatment.
Getting Accutane through a traditional pharmacy can mean delays, stock issues, and insurance headaches. Clear Health partners with FDA-regulated specialty pharmacies that focus on dermatology medications, ensuring reliable access, faster fulfillment, and seamless iPLEDGE compliance.
No unnecessary wait times—just affordable and hassle-free treatment.
Customer support is on it! Always helping me with things I need and ask. Also, their quick replies are amazing. I'm just grateful! Never thought I'll be getting accutane online. So much easier!
My experience has been great so far
Amanda B.
My experience has been great so far! Easy to message my doctor with any questions and I was able to get on Accutane so much faster than if I’d made an in-person appointment. Their pharmacy also offers great pricing that ended being the cheaper option vs my insurance. I highly recommend clear health.
Great Company! Wonderful Services!
D HB.
Very fast and helpful assistance from all staff members. Customer service is always there to assist me and the doctors I have worked with have been stellar and just as responsive. They have many resources at your disposal to assist as well.
Clear Health has been very responsive…
BIBI
Clear Health has been very responsive to my questions in a short time span as well as having a very courteous approach.
Amazing and revolutionary acne treatment
Sanjana D.
Its a great and cheap way to get one of the most expensive treatments for acne out there. The support is amazing, they really go out of their way to answer any questions you may have or address any concerns. The doctor too is readily available. I very highly recommend clear Health. Trust me
Smooth and easy process
MELISS
Smooth and easy process. Especially helpful with clearing hoops like prior authorization and communicating with pharmacy. I’m very appreciative of clear and glad I found them.
Super responsive customer support
ERICA D.
Super responsive customer support! The experience has been great for my daughter and so much easier than waiting months and months to see a dermatologist in person.
So much easier and quicker than going…
JACKIE M.
So much easier and quicker than going through the in-person experience. This is my 2nd time going on Accutane, and I love how everything is organized in the online portal. Pills were also much cheaper than my local CVS and I was even able to get BC directly from my Clear physician!
I'm very pleased with Clear Health
Shaban R.
I'm very pleased with Clear Health! Everything was wonderful, from the initial online consultation to the monthly order that I receive in the mail. I would absolutely recommend them to anyone looking to take better care of their skin.
*Individual results vary
<span>Standard Protocol</span> Ingredients
Important Pregnancy and Breastfeeding Warning for Spironolactone
Spironolactone Pregnancy Warnings:
Use is considered contraindicated; use during pregnancy requires the benefit be weighed against the risk to the fetus.
US FDA pregnancy category: C
Comments: Adequate methods of contraception should be encouraged.
Animal studies have revealed an increased resorption rate, decreased live fetuses, and progestational and antiandrogenic effects. There are no controlled data in human pregnancy.
US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Spironolactone Breastfeeding Warnings:
A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
Excreted into human milk: Yes (as active metabolite) According to some authorities, use of this drug appears acceptable during breastfeeding.