Introducing
Isoclear™
topical Isotretinoin gel system
The Hollywood Dose
Micro-dose Protocol
for resistant acne
Who We Are
Our Story
FAQs
Contact Us
Blog
Explore
Success Stories
Standard Accutane vs Micro-dose Protocol
Pay over time with
For Emergencies:
Need emotional support? (24/7): Call or text 988
Emergency Services (24/7): Dial 911
View All
Isotretinoin (Accutane) Protocols
Standard Protocol
Micro-dose Protocol
Oral and Topical Treatments
Isoclear™
NewDoxycycline + Topical
Spironolactone + Topical
Compounded Topical
Supporting Products
Jojoba Oil Cleanser
Lightweight Moisturizer
Home Pregnancy Tests (6 ct)
Aquaphor (3 ct)
At-Home LFT + Lipid Panel Bloodwork Kit
Who We Are
Our Story
FAQs
Contact Us
Blog
Explore
Success Stories
Standard Accutane vs Micro-dose Protocol
Pay over time with
For Emergencies:
Need emotional support? (24/7): Call or text 988
Emergency Services (24/7): Dial 911
Isoclear™
RxA proprietary dermatologist-guided topical isotretinoin system — featuring the active ingredient in Accutane — designed to treat acne, fade marks, and maintain clear skin, without the complexity of oral treatment.
This product is a compounded formulation prepared by a licensed pharmacy pursuant to Section 503A of the Federal Food, Drug, and Cosmetic Act. Compounded medications are not FDA-approved, meaning they have not been evaluated by the FDA for safety, effectiveness, or quality. Licensed medical providers may prescribe compounded preparations at their professional discretion based on an individual patient’s needs. This product is intended for use only under medical supervision.
I'd tried four other things for seven years. By the time I started Isoclear I was honestly out of patience. I'm glad I gave it one more try.
From active breakouts to lingering marks, not all treatments work the same. Compare how each approach targets acne, oil, and long-term skin health.
Comparison
Targets Root Cause
Targets Marks & Texture
No iPLEDGE Required
No Monthly Check-ins
No Lab Tests Needed
(Clear Health)
All-in-one system starting at $50/mo
(Generic Platforms)
$60–$100+/mo across multiple products
(Clear Health)
Starts from $59/mo (Evaluation Only)
Swipe to compare
A personalized approach to clearer skin. Start with your primary concern - acne, marks, or anti-aging and let Isoclear™ adjust to your needs.
PHASE 1 • 0-4 MONTHS
A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.
PHASE 1 • 0-4 MONTHS
PHASE 2 • 4-6 MONTHS
A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.
PHASE 2 • 4-6 MONTHS
PHASE 3 • 6 MONTHS +
A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.
PHASE 3 • 6 MONTHS +
A personalized approach to clearer skin. Start with your primary concern - acne, marks, or anti-aging and let Isoclear™ adjust to your needs.
PHASE 1 • 0-4 MONTHS
PHASE 2 • 4-6 MONTHS
PHASE 3 • 6 MONTHS +
Target breakouts at the source.
Fight post-acne marks and uneven skin tone.
Where clear skin becomes great skin.
The Clear phase focuses on active breakouts at the source, helping to regulate sebum production, increase cellular turnover, and fight bacteria and inflammation.
The Fade phase targets post-inflammatory hyperpigmentation (PIH) once breakouts clear, while evening out skin tone for a uniform glow.
Keep breakouts at bay while improving skin texture and renewing your skin’s vitality with a peptide complex and GHK-Cu (Copper Peptide).
A Vitamin A derivative that controls sebum, boosts cell turnover, and reduces inflammation. The active ingredient in oral Accutane.
Weeks to statistically significant improvement vs. placebo, 268-patient trial
Chalker DK, Lesher JL, Smith JG, et al. J Am Acad Dermatol. 1987;17(2):251–254. Multicenter, double-blind, vehicle-controlled trial of topical isotretinoin 0.05% gel (N = 268). View Study Individual results may vary.
*Data shown is derived from studies on topical isotretinoin formulations in clinical settings, not Isoclear™ specifically.
Access personalized treatment, prescription management, and ongoing support, all in one streamlined plan.
Clear, upfront pricing with no hidden fees or surprise charges, so you always know exactly what's included in your treatment plan.
Track your acne journey with progress photos, treatment check-ins, and access to your intake history throughout care. If your doctor recommends changing or adjusting your treatment, it's included at no additional consultation cost.
Get access to expert acne treatment without insurance, referrals, or in-person appointments.
Choose a payment option that fits your budget. Affirm financing with 0% APR options is available on eligible plans.
Get expert dermatology care from anywhere in the U.S., with no in-person visits required.
Not seeing the results you want with Isoclear™ after 4 months? We'll help you step up to oral Accutane or an alternative treatment if appropriate - including your first month's consult and medication FREE on us (up to a $174 value).
Annual
Continuous treatment access for 12 months*
Billed $480 every 12 months
Bi-Monthly
Everything for your treatment, in one price
Starting with a 2-month supply
We get it – starting a new acne treatment can be full of uncertainty and questions. Will it work for you? How long will results take?
Our goal is to get you clear. If you use Isoclear™ for at least 4 months and aren’t seeing the progress you want, we’ll help you step up to oral Accutane - on us to get started, including your first month’s consult and medication (up to a $174 value).
A derivative of Vitamin A that works by controlling sebum production, increasing cellular turnover, and reducing inflammation. Isotretinoin is the active ingredient in oral Accutane.
Clindamycin is a topical antibiotic that reduces acne-causing bacteria and helps calm inflammation in the skin.
Vitamin B3 that controls oil, brightens skin, and strengthens the barrier—reducing redness for balanced, healthier skin.
A copper peptide that helps support skin repair and collagen production, improving firmness and overall skin quality.
Small amino-acid signaling molecules that help smooth expression lines, fine lines, and wrinkles.
A skin-brightening ingredient that helps reduce hyperpigmentation (like melasma and dark spots) by interfering with pathways that trigger excess melanin production.
Starts at$50/mo
Evaluations start at$59/mo
1st month starts at$59
$28
$28
from$30/mo
$37.50/mo
$40/mo
$115
$30
$30
Oral Accutane vs. Isoclear (Topical Isotretinoin)
If you’ve followed Clear Health for any amount of time, you probably know that we started with Accutane. There’s a reason for that. I struggled with acne myself, tried .....
DESIGNED BY DERMATOLOGISTS
Isoclear™ is built for people who’ve tried everything else. Doctor-guided. Delivered to your door.
Free consult if you're not eligible
